Domestic laboratory spray freeze dryer developed successfully
The China Drying Newsletter Spray Freeze Dryer is a revolutionary new development in the 21st century. It combines the advantages of spray drying and freeze drying, while effectively avoiding the disadvantages of both, as opposed to freeze dryers, sprays. The freeze dryer consumes less energy and conforms to the low-carbon requirements. The dried sample is granular and has very good fluidity. It does not need to be crushed again. Compared to the spray dryer, the spray freeze dryer has less damage to the nutrients. , And does not change the biological activity, application is broader. In foreign countries, Spray Freeze Drying (SFD) technology has been applied to pharmaceutical microcapsule technology and the production of milk powder is increasing. In particular, previous drug microcapsules mainly rely on spray drying technology, but the spray drying process is a high temperature drying process. In the process, many heat-sensitive drugs will have physical and even chemical changes that affect the actual composition of the drug. Spray freeze-drying technology mainly combines spray freezing and freeze-drying technologies. Compared with traditional freeze-drying technology, SFD has the following advantages: (1) atomized and dispersed fine droplets quickly freeze when immersed in low temperature, can weaken the growth of ice crystals, reduce ice crystal damage to liposomes, and avoid drug leakage And sudden release; (2) Freeze the sample after vacuum drying to form a spherical particle with a microporous structure, the fluidity is good, and the size of the particle can be adjusted by changing the spray process. Shanghai Yacheng Instrument Equipment Co., Ltd. successfully developed a laboratory spray freeze dryer YC-3000, which fills the gap in the field of domestic laboratory spray freeze-drying R&D equipment. Suitable for completely simulating the whole process of spray freezing in the laboratory, can be used in the laboratory for original formulation determination/formula renewal, taste screening, color evaluation, stabilizer/emulsifier application, shelf life testing, and production of complimentary customer samples. Experimental data can be directly amplified for industrial production. It is suitable for low-temperature drying of heat-sensitive, viscous, active materials and materials with high sugar content, such as natural product extracts of Chinese herbal medicines, dairy products, biological agents, enzyme preparations, fruit juices, and polymer materials. YC-3000 Laboratory Spray Freeze Dryer Main Features 1. The laboratory spray freeze dryer combines the organic drying of spray drying and vacuum freeze drying. The required drying time is very short, which greatly shortens the traditional vacuum freeze-drying time, and the dried material is powdery. Solids, spray freeze-dried items, the original biological and chemical properties of the basic unchanged, easy to long-term preservation, after adding water can be restored to the state before freeze-dried, and can maintain its original biochemical characteristics; 2. The equipment adopts an air-cooled condensing totally-enclosed compressor refrigeration system, which has rapid cooling, low icing temperature, strong moisture absorption capacity, and digital and accurate display of temperature and vacuum degree. 3. The frozen spray-dried articles are sublimated by natural air heating to maintain the safety of the samples; 4, the host is equipped with a vacuum pump power plug, without additional power, easy to use; 5, vacuum connection using international standard clamps, convenient and reliable; 6, stable performance, easy operation, low noise; 7. Quick freeze spray drying contrasts with traditional freeze dryer: It can quickly freeze-dried the liquid materials with easy-to-stick walls and organic substances (juice, Chinese medicine extract, etc.), and the dried finished product is in a granular state with good fluidity. The particle size can be adjusted within a certain range.
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