Ultra-low temperature micro powder preparation complete sets of equipment included in the 2006 Zhejiang Science and Technology Plan key scientific research projects

The ultra-low temperature micro-powder preparation equipment for bio-pharmaceutical engineering jointly developed by Zhejiang Fengli Crushing Equipment Co., Ltd., a national key high-tech enterprise, and the 609th Research Institute of China National Aviation Industry Corporation, was recently included in the 2006 Zhejiang Provincial Science and Technology Plan key scientific research projects (plan number : 2006C21056). The development of this project will solve the comminution problem of biopharmaceutical materials that are difficult to smash at room temperature, and provide new equipment for the production of high value-added powder materials to the biomedical engineering industry in China. It has considerable economic benefits and a huge society. benefit.

Ultra-low temperature comminution technology is one of the most important powder processing technologies and has been widely used in new drug development, health product development, bio-engineering, food processing and other industries. Ultra-low temperature comminution is to freeze the difficult-to-grind material below the embrittlement point at room temperature, and then it is crushed to the required fineness in the grinder, and the original composition will not be destroyed. The cryogenic comminution process uses liquid nitrogen or air as the cooling medium for comminution. The low-temperature freezing using liquid nitrogen as a refrigerant is expensive, and it is difficult to use the product with a low added value. The cryogenic comminution using air cooling is much less expensive than the cryogenic comminution of liquid nitrogen refrigeration. According to China's national conditions, the use of air as a cooling medium cryogenic crusher and complete sets of equipment is the new subject we want to study. At present, China's ultra-low temperature micro-powder preparation technology has not yet been formed, and Japan and other countries have taken measures to block such technologies. The development of ultra-low temperature micro-powder preparation technology in China has become one of the most critical approaches to improving the preparation technology of traditional Chinese medicine.

Zhejiang Fengli will have its own intellectual property rights after successfully developing this complete set of equipment. Its innovation lies in the organic combination of air-turbine expansion ultra-low temperature cooling device and crusher, reflecting the integrity of the system, greater energy-saving effect and good crushing characteristics; The use of a reasonable crushing gap, tool shape, smashing structure to achieve the ideal crushing effect; select the appropriate ultra-low temperature steel to ensure the stability of the equipment; use of automatic control system, to achieve a good man-machine interface control.

The complete set of equipment uses the air-based ultra-low temperature freezer made of aerospace technology to crush materials that are difficult to crush at room temperature, such as Chinese herbal medicines, high value-added foods, animal bones, and high-value biological materials, such as heat-sensitive and heat-prone materials. The easily decomposable substances are greatly improved in the fineness of these substances through low-temperature crushing; and they can be selectively crushed by using different brittle temperatures of the materials, and finally they are separated into pure and single powders. Its promotion and application not only provides ideal cryogenic comminuting processing equipment for these industries, but also increases the core competitiveness of related industries due to the breakthrough of common technology: if the ultrafine powder material of Chinese medicine is made, it will effectively improve the efficacy of the product; The ultrafine powder material of the bioengineering industry will greatly increase the absorption of various health products.